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Denumire
Twinvir ™ - medicament antiviral combinat.

Compozitie
Un comprimat Twinvir ™ con?ine Ledipasvir - 90 mg ?i Sofosbuvir - 400 mg.

Indica?ii pentru utilizare
Combina?ia de Ledipasvir ?i Sofosbuvir este indicata pentru tratamentul hepatitei C de genotip 1, 4, 5 ?i 6 la adul?i.

Continutul ambalajului
28 comprimate filmate.

Doze si mod de administrare
Doza recomandata: se administreaza oral cate o tableta (Ledipasvir 90 mg ?i Sofosbuvir 400 mg) o data pe zi. Durata recomandata a tratamentului pentru pacien?ii fara experien?a de raspuns negativ la tratament: 12 saptamani. Cu experien?a de raspuns negativ la terapie (fara ciroza): 24 saptamani. Cu experien?a de raspuns negativ la terapie (cu ciroza hepatica): 24 saptamani.

Interactiunea cu alte medicamente
Utilizarea medicamentului impreuna cu amidarona poate provoca bradicardie. Inductorii P-gp (rifampicina, rifabutina, sunatoare, carbamazepina, fenobarbital ?i fenitoina) reduc concentra?ia de Ledipasvir ?i Sofosbuvir in sange, scazand astfel eficienta tratamentului.

Utilizarea in timpul sarcinii ?i alaptarii
Nu sunt disponibile date privind efectul medicamentului asupra dezvoltarii fetului ?i alaptarii. In timpul sarcinii ?i alaptarii, medicamentul poate fi prescris doar de catre medicul curant.

Utilizare in pediatrie
Siguran?a ?i eficacitatea a combina?iei de Ledipasvir ?i Sofosbuvir la pacien?ii cu varsta sub 18 ani nu au fost studiate.

Descrierea medicamentului
Twinvir ™ este disponibil sub forma de tablete pentru administrare orala. Compozi?ia include doua componente active: Ledipasvir, care este un inhibitor al proteinei virale ?i, de asemenea, Sofosbuvir, un inhibitor al ARN polimerazei.

Atentionari si precautii
Bradicardia poate sa apara la pacien?ii trata?i cu amiodarona, mai ales la cei care administreaza amiodarona concomitent cu alte medicamente care incetinesc ritmul cardiac. Nu se recomanda administrarea concomitenta a amiodaronei ?i combina?ia Ledipasvir si Sofosbuvir. Monitorizarea cardiaca este recomandata pacien?ilor fara op?iuni terapeutice alternative. Pacientilor cu insuficien?a renala severa sau insuficien?a renala in stadiu terminal, doza se calculeaza de catre medicul curant. Utilizarea Twinvir ™ cu alte medicamente care con?in Sofosbuvir nu este recomandata.

Site: https://twinvir.ro

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Gość

 
1908年 - ハーバート・ヘンリー・アスキスがイギリスの第52代首相に就任。 江ノ島駅で「江ノ電カレンダー」を購入し、午後3時頃に鎌倉方面行きの江ノ電に乗り鎌倉駅に降りた。 ヤマハ 116 アイアン
放送事業の持ち株会社は全国で9社目で、テレビやラジオ放送の系列事業会社を傘下に持つ予定だ。 途中、刈谷ハイウェイオアシス(刈谷PA)にて高速道路情報を確認。
タイトリスト AP3 同氏は今回の研究の意義について、脳の信号を検知してこれを脚の動きにつなげることが可能だと初めて示されたと指摘する。 民の犠牲は、自分たちの保身のためには、当然だとみなしてきたのです。
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そして食べるものがなくなると、人食いをはじめるでしょう。 彼ならではの絢爛(けんらん)を極めたビジュアルも見ものでした。 718 MB
<きゅうりの辛子漬>  毎度おなじみの漬物! 漬物は必ず冷蔵庫で保存してくださいね。 間違いなくウォリァーズのスィープだったでしょう。
ミズノ JPX900 今回の試合でもどのような結果が出るかは分からないが、基準点よりも得点が出円多少難しく見えて、それでも直前シカゴ試合後の二日間の休息後、試合と勝利を得るには、不足がないようだ。 面白いのが、昔、この沼に首が馬、体が牛の魚獣がいたから、というのがあった。
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